@vulcanjedi - James and Nime5ter already have suggested most of the things I can think of. Did you try the Amulet remote with your Win 10 laptop? Did it work as a microphone (could you record audio using Sound Recorder?)?
Here's something I would try at this point:
What is the version of Oracle Virtualbox you're using? If it isn't the latest, can you try upgrading it to the latest (5.0.6 right now)? To upgrade, it only takes a download and an install, as you'd do if it were the first time. The guest VM definition and virtual OS disk is preserved across the upgrade. After this install,
1. make sure you also install Virtualbox's companion "extension pack" for the corresponding version of Virtualbox and
2. Install and upgrade the "guest additions" within the guest VM using the CD ISO image that Virtualbox provides.
3. Reboot the VM and try the Amulet as a microphone.
Also, I hope you are not creating the USB filters by hand. The filters should appear under USB configuration in Virtualbox automatically, once the Amulet USB dongle is plugged in. At this point, you should have to just enable the checkbox against the filter. If you upgrade as described above, try to remove all USB filters, reboot VM and re-create the filters by plugging in the Amulet dongle.
-Ajith
@Nime5ter - those are some very kind words you mentioned about me