Just keep in mind that if, in some of your commands, you refer to payload xml files or other programs using absolute file paths instead of relative paths, you may have to go in and edit those commands to correct the file paths on the new computer.
Also, James usually suggests that people
purge their caches and
restart VC in these cases as a precaution.
http://voxcommando.com/mediawiki/index.php?title=Main_Menu#FileIt's not strictly necessary, but it's a good idea -- particularly for people who may have different speech engines on their different computers or who are trying to merge two different command trees (not for newbies!), etc.